Very common (≥1/10): Headache, nausea, vomiting, myalgia, arthralgia and joint stiffness, injection site pain, fatigue, chills, pyrexia, lymphadenopathy, injection site swelling and erythema.
Common (≥1/100 to <1/10): Rash, injection site erythema or swelling, vomiting, diarrhoea.
Uncommon (≥1/1000 to <1/100): Injection site pruritus.
Rare (≥1/10000 to <1/1000): Facial swelling, acute peripheral facial paralysis.Frequency not known: Anaphylaxis, hypersensitivity; however, anaphylactic reactions following vaccination are extremely rare.
Myocarditis and Pericarditis
Reports indicate an increased risk of myocarditis and pericarditis, particularly following the administration of the second dose of the Moderna COVID-19 vaccine. Typically, symptoms onset within a few days following vaccination. Caution should be exercised when prescribing the Moderna COVID-19 vaccine to individuals with a history of myocarditis or pericarditis.Seek immediate medical attention at a hospital or healthcare facility if any of the following signs occur:
- Oral symptoms: Numbness around the lips or tongue;
- Dermal symptoms: Rash, red spots, cyanosis, skin redness, bleeding, or subcutaneous haemorrhage;
- Throat symptoms: Itching, tightness, feeling of throat constriction, or dysphonia/difficulty speaking;
- Neurological symptoms: Prolonged or severe headache, lethargy, somnolence, confusion, coma, or seizures;
- Cardiovascular symptoms: Chest pain, prolonged palpitations, or syncope;
- Gastrointestinal symptoms: Vomiting, abdominal cramps, or diarrhoea;
- Respiratory symptoms: Dyspnoea, stridor, wheezing, or cyanosis;
- Systemic symptoms:
- Dizziness, lightheadedness, feeling faint, or unusual fatigue.
- Unusually severe pain in one or more areas not caused by trauma or injury.
- Persistent high fever exceeding 38.5°C that does not respond to antipyretics.
Note:
+ Ensure 24/7 assistance by a caregiver, at least during the first 3 days following COVID-19 vaccination.
+ Avoid alcohol and stimulants for at least the first 3 days post-vaccination.
+ Maintain adequate nutrition.
+ If swelling, redness, pain, or a small lump appears at the injection site: Continue monitoring. If the swelling rapidly increases in size, seek medical evaluation immediately. Do not apply ointments, compresses, or any substances to the swollen and painful area.
+ Regularly monitor body temperature. If:
- Fever is below 38.5°C: Remove or loosen clothing, apply warm compresses/wipes to the forehead, armpits, and groin, and ensure adequate fluid intake. Prevent chilling. Recheck temperature after 30 minutes.
- Fever is 38.5°C or higher: Administer antipyretics as directed by healthcare personnel. If the fever cannot be brought down or recurs within 2 hours, notify medical personnel immediately and report to the nearest healthcare facility.